Oth D
Biomedicine. 1975 Sep;22(5):350-7.
The main methods for detecting the tumour associated antigens of chemically-induced tumours, and the significance of the results given by these methods are briefly reviewed. The possibility of finding several sorts of tumour antigens is discussed more specifically. The origin of the antigenically unique (non-crossing) antigens found in the chemically-induced tumours, as compared to the frequently cross-reacting antigens found in the virus-induced tumours, gives rise to speculation. The biological significance of these antigens is discussed.
简要回顾了检测化学诱导肿瘤相关抗原的主要方法以及这些方法所得结果的意义。更具体地讨论了发现多种肿瘤抗原的可能性。与病毒诱导肿瘤中常见的频繁交叉反应抗原相比,化学诱导肿瘤中发现的抗原性独特(非交叉)抗原的起源引发了猜测。还讨论了这些抗原的生物学意义。