• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. 3. Regional distribution of pimozide and of haloperidol in the dog brain.

作者信息

Janssen P A, Soudijn W, van Wijngaarden I, Dresse A

出版信息

Arzneimittelforschung. 1968 Mar;18(3):282-7.

PMID:5696000
Abstract
摘要

相似文献

1
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. 3. Regional distribution of pimozide and of haloperidol in the dog brain.
Arzneimittelforschung. 1968 Mar;18(3):282-7.
2
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. II. Kinetic study of the distribution of pimozide and metabolites in brain, liver, and blood of the Wistar rat.匹莫齐特，一种化学结构新颖、高效且口服长效的抗精神病药物。II. 匹莫齐特及其代谢产物在Wistar大鼠脑、肝和血液中分布的动力学研究。
Arzneimittelforschung. 1968 Mar;18(3):279-82.
3
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.匹莫齐特，一种化学结构新颖、高效且口服长效的抗精神病药物。I. 匹莫齐特、氟哌啶醇和氯丙嗪的比较药理学。
Arzneimittelforschung. 1968 Mar;18(3):261-79.
4
The distribution of the butyrophenones haloperidol, trifluperidol, moperone, and clofluperol in rats, and its relationship with their neuroleptic activity.丁酰苯类药物氟哌啶醇、三氟哌啶醇、莫哌隆和氯氟哌隆在大鼠体内的分布及其与它们抗精神病活性的关系。
Arzneimittelforschung. 1969 Feb;19(2):199-208.
5
Clopimozide (R 29 764), a new highly potent and orally long-acting neuroleptic of the diphenylbutylpiperidine series.氯哌莫齐（R 29 764），一种新型高效且口服长效的二苯基丁基哌啶系列抗精神病药。
Arzneimittelforschung. 1975 Aug;25(8):1287-94.
6
The metabolism and excretion of the neuroleptic drug pimozide (R 6238) by the wistar rat.抗精神病药物匹莫齐特（R 6238）在Wistar大鼠体内的代谢与排泄
Life Sci. 1969 Mar 1;8(5):291-5. doi: 10.1016/0024-3205(69)90279-3.
7
[Clinical possibility of therapeutic evaluation in pharmacotherapy: efficacy test of a new long-acting neuroleptic, "Pimozide"].[药物治疗中治疗评估的临床可能性：新型长效抗精神病药“匹莫齐特”的疗效测试]
Psychiatr Neurol Med Psychol (Leipz). 1971 Jun;23(6):359-67.
8
Distribution, excretion and metabolism of neuroleptics of the butyrophenone type. I. Excretion and metabolism of haloperidol and nine related butyrophenone-derivatives in the Wistar rat.丁酰苯类抗精神病药物的分布、排泄及代谢。I. 氟哌啶醇及九种相关丁酰苯衍生物在Wistar大鼠体内的排泄与代谢
Eur J Pharmacol. 1967 Jan;1(1):47-57. doi: 10.1016/0014-2999(67)90065-9.
9
Enhanced sensitivity to pentobarbital in haloperidol or pimozide treated mice and rats.
Res Commun Chem Pathol Pharmacol. 1980 May;28(2):267-84.
10
The dopamine-releasing actions of neuroleptics and ethanol.抗精神病药物和乙醇的多巴胺释放作用。
J Pharmacol Exp Ther. 1974 Jul;190(1):131-40.

引用本文的文献

1
Determination of oxidative stress and activities of antioxidant enzymes in guinea pigs treated with haloperidol.用氟哌啶醇治疗的豚鼠氧化应激及抗氧化酶活性的测定
Exp Ther Med. 2013 Feb;5(2):479-484. doi: 10.3892/etm.2012.822. Epub 2012 Nov 20.
2
Neuroleptic drugs in the human brain: clinical impact of persistence and region-specific distribution.人脑中的抗精神病药物：持续性和区域特异性分布的临床影响
Eur Arch Psychiatry Clin Neurosci. 2006 Aug;256(5):274-80. doi: 10.1007/s00406-006-0661-7.
3
Region specific distribution of levomepromazine in the human brain.
左美丙嗪在人脑中的区域特异性分布。
J Neural Transm (Vienna). 2006 Mar;113(3):387-97. doi: 10.1007/s00702-005-0331-3. Epub 2005 Jul 6.
4
Calcium channel activity in rat brain synaptosomes: effects of neuroleptics and other factors regulating phosphorylation and transmitter release.
Neurochem Res. 1984 Jan;9(1):109-20. doi: 10.1007/BF00967663.
5
Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.二苯基丁基哌啶类抗精神分裂症药物作为钙通道拮抗剂发挥作用。
Proc Natl Acad Sci U S A. 1983 Aug;80(16):5122-5. doi: 10.1073/pnas.80.16.5122.
6
The distribution of haloperidol in rat brain.氟哌啶醇在大鼠脑中的分布。
Br J Pharmacol. 1969 May;36(1):208P-209P.
7
Neurometabolic and behavioural effects of haloperidol in relation to drug levels in serum and brain.氟哌啶醇的神经代谢及行为效应与血清和脑内药物水平的关系
Naunyn Schmiedebergs Arch Pharmacol. 1977 Sep;299(2):105-14. doi: 10.1007/BF00498552.
8
Pimozide: a review of its pharmacological properties and therapeutic uses in psychiatry.匹莫齐特：其药理学特性及在精神病学中的治疗用途综述
Drugs. 1976;12(1):1-40. doi: 10.2165/00003495-197612010-00001.