应用于威尔逊氏病的生物材料中铜的中子活化分析。
Neutron activation analysis ofr copper in biological material applied to Wilson's disease.
作者信息
Fell G S, Smith H, Howie R A
出版信息
J Clin Pathol. 1968 Jan;21(1):8-11. doi: 10.1136/jcp.21.1.8.
Abstract
A method for the neutron activation analysis of copper in biological material is described and applied to the diagnosis and management of four cases of Wilson's disease. Results obtained for serum and urine are in agreement with values obtained by established colorimetric techniques. The method described can estimate 10(-9) g. copper to within 10% and this sensitivity has allowed the determination of copper from biopsy material such as liver, spleen, hair, and nail.
摘要
本文描述了一种用于生物材料中铜的中子活化分析方法，并将其应用于4例威尔逊病的诊断和治疗。血清和尿液的检测结果与既定比色技术所获值一致。所述方法可将铜含量估计至10⁻⁹ g，误差在10%以内，这种灵敏度使得能够测定来自肝脏、脾脏、毛发和指甲等活检材料中的铜含量。
相似文献
1
Neutron activation analysis ofr copper in biological material applied to Wilson's disease.应用于威尔逊氏病的生物材料中铜的中子活化分析。
J Clin Pathol. 1968 Jan;21(1):8-11. doi: 10.1136/jcp.21.1.8.
2
Tissue copper, zinc, and manganese levels in Wilson's disease: studies with the use of neutron activation analysis.
J Lab Clin Med. 1971 Mar;77(3):438-44.
3
[Use of neutron activation analysis in the diagnosis and follow-up studies of Wilson's disease].[中子活化分析在威尔逊病诊断及随访研究中的应用]
Klin Wochenschr. 1971 Mar 1;49(5):284-6. doi: 10.1007/BF01485434.
4
Prevention of Wilson's disease in asymptomatic patients.无症状患者威尔逊病的预防。
N Engl J Med. 1968 Feb 15;278(7):352-9. doi: 10.1056/NEJM196802152780702.
5
Muscle copper, zinc, and manganese levels in Wilson's disease: studies with the use of neutron-activation analysis.威尔逊病患者肌肉中铜、锌和锰的含量：采用中子活化分析法的研究
J Lab Clin Med. 1970 Sep;76(3):432-8.
6
Studies with radioactive copper (64Cu and 67Cu) in relation to the natural history of Wilson's disease.
Lancet. 1967 Feb 8;1(7486):346-50. doi: 10.1016/s0140-6736(67)92893-0.
7
[True hepatic Wilson's disease].[真性肝豆状核变性]
Pediatr Med Chir. 1983 Mar-Apr;5(1-2):7-10.
8
[Wilson's disease. Introduction to current problems (early diagnosis and therapy)].[威尔逊氏病。当前问题介绍（早期诊断与治疗）]
Wien Z Inn Med. 1967;48(12):461-5.
9
10
Chronic hepatitis as a first manifestation of Wilson's disease.慢性肝炎作为威尔逊病的首发表现。
Ann Intern Med. 1972 Jan;76(1):59-64. doi: 10.7326/0003-4819-76-1-59.
引用本文的文献
1
2
Prion fragment peptides are digested with membrane type matrix metalloproteinases and acquire enzyme resistance through Cu²⁺-binding.朊病毒片段肽被膜型基质金属蛋白酶消化，并通过结合铜离子获得酶抗性。
Biomolecules. 2014 May 8;4(2):510-26. doi: 10.3390/biom4020510.
3
Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases.威尔逊病和血色素沉着症（氧化应激过载疾病）患者非肿瘤性人类肝脏中p53突变负荷增加。
Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12770-5. doi: 10.1073/pnas.220416097.
4
The cardiomyopathy of Wilson's disease. Myocardial alterations in nine cases.威尔逊氏病的心肌病。9例心肌改变。
Virchows Arch A Pathol Anat Histol. 1982;397(3):301-11. doi: 10.1007/BF00496571.
本文引用的文献
1
Copper content of hair and nails in Wilson's disease (hepatolenticular degeneration).威尔逊病（肝豆状核变性）患者头发和指甲中的铜含量
Metabolism. 1961 Dec;10:1085-7.
2
AN ABSORPTIOMETRIC METHOD FOR THE DETERMINATION OF TRACES OF COPPER IN BIOLOGICAL MATERIALS WITH DITHIZONE.用双硫腙测定生物材料中痕量铜的吸收光度法。
Clin Chim Acta. 1965 May;11:452-60. doi: 10.1016/0009-8981(65)90193-2.
3
Simple procedure for the single sample determination of serum copper and iron.血清铜和铁单样本测定的简单程序。
Clin Chim Acta. 1958 Jul;3(4):328-34. doi: 10.1016/0009-8981(58)90021-4.
4
Abnormalities of copper metabolism in Wilson's disease and their relationship to the aminoaciduria.威尔逊病中铜代谢异常及其与氨基酸尿症的关系。
J Clin Invest. 1954 Mar;33(3):400-9. doi: 10.1172/JCI102912.
Zotero 插件