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用于血浆纤维蛋白原测定的乳胶结合抗纤维蛋白原试验。

Latex-bound antifibrinogen test for plasma fibrinogen assay.

作者信息

Castelan D J, Hirsh J, Martin M

出版信息

J Clin Pathol. 1968 Sep;21(5):638-42. doi: 10.1136/jcp.21.5.638.

DOI:10.1136/jcp.21.5.638
PMID:5697369
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473879/
Abstract

The semiquantitative latex-bound antifibrinogen test (Fi test) can be modified to quantitate plasma fibrinogen. The test is rapid and simple and does not require complex apparatus. Although the Fi reagent reacts with early fibrinogen and fibrin breakdown products, the degree of interference is not marked and the test is sufficiently accurate to be of clinical value as a fibrinogen assay in patients with increased fibrinolytic activity.

摘要

半定量乳胶结合抗纤维蛋白原试验（Fi试验）可进行改良以定量血浆纤维蛋白原。该试验快速简便，无需复杂仪器。尽管Fi试剂可与早期纤维蛋白原及纤维蛋白降解产物发生反应，但干扰程度并不显著，且该试验准确性足以使其作为纤溶活性增加患者纤维蛋白原测定方法具有临床价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2226/473879/ff4c1ec59962/jclinpath00376-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2226/473879/ff4c1ec59962/jclinpath00376-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2226/473879/ff4c1ec59962/jclinpath00376-0101-a.jpg

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本文引用的文献

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Rapid estimation of plasma fibrinogen concentration and its use as a guide to therapy of intravascular defibrination.
Am J Obstet Gynecol. 1952 Jul;64(1):141-7. doi: 10.1016/s0002-9378(16)38744-0.
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A new method for the determination of fibrinogen in small samples of plasma.一种测定少量血浆样本中纤维蛋白原的新方法。
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EFFECT OF FIBRIN AND FIBRINOGEN PROTEOLYSIS PRODUCTS ON CLOT PHYSICAL PROPERTIES.纤维蛋白和纤维蛋白原蛋白水解产物对血凝块物理特性的影响。
采用新型抗体包被乳胶颗粒检测纤维蛋白原 - 纤维蛋白降解产物。
J Clin Pathol. 1972 Aug;25(8):680-2. doi: 10.1136/jcp.25.8.680.
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A SIMPLE METHOD FOR THE INSTANTANEOUS QUANTITATION OF FIBRINOGEN THE FPT-TEST.
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Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment.人血清中纤维蛋白原裂解产物的定量测定及其与诊断和治疗的关系
Blood. 1966 Jul;28(1):1-18.
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Platelet function in a patient with thrombasthenia.血小板无力症患者的血小板功能
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Determination of fibrinogen and fibrinolysis products in human plasma by an immunochemical method.用免疫化学方法测定人血浆中的纤维蛋白原和纤维蛋白溶解产物。
Scand J Clin Lab Invest. 1965;17(4):341-8. doi: 10.3109/00365516509077061.
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Fibrinogenolytic dysfibrinogenemias.纤维蛋白原溶解异常的异常纤维蛋白原血症
Fed Proc. 1965 Jul-Aug;24(4):822-6.