胰蛋白酶活性中心的疏水相互作用。疏水结合位点对脒基型竞争性抑制剂侧链修饰的敏感性。 - Suppr

Hydrophobic interactions in the trypsin active center. The sensitivity of the hydrophobic binding site to side chain modifications in competitive inhibitors of the amidinium type.

作者信息

Mares-Guia M

出版信息

Arch Biochem Biophys. 1968 Sep 20;127(1):317-22. doi: 10.1016/0003-9861(68)90232-4.

DOI:10.1016/0003-9861(68)90232-4

PMID:5697989

Abstract

摘要

相似文献

Hydrophobic interactions in the trypsin active center. The sensitivity of the hydrophobic binding site to side chain modifications in competitive inhibitors of the amidinium type.

Arch Biochem Biophys. 1968 Sep 20;127(1):317-22. doi: 10.1016/0003-9861(68)90232-4.

Thermodynamics of the hydrophobic interaction in the active center of trypsin. Investigation with amidines and guanidines.

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STUDIES ON THE ACTIVE CENTER OF TRYPSIN. THE BINDING OF AMIDINES AND GUANIDINES AS MODELS OF THE SUBSTRATE SIDE CHAIN.

J Biol Chem. 1965 Apr;240:1579-85.

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Changes in the exposure of the tyrosyl and tryptophyl residues in trypsin due to diisopropylphosphoryl and benzamidine inhibition.

Biochemistry. 1971 Nov 23;10(24):4589-94. doi: 10.1021/bi00800a037.

Proteolytic enzymes. VI. Aromatic amidines as competitive inhibitors of trypsin.

J Biochem. 1971 May;69(5):893-9. doi: 10.1093/oxfordjournals.jbchem.a129540.

Chemical modifications of amino groups of trypsin.

Biochem Biophys Res Commun. 1969 Sep 10;36(6):999-1005. doi: 10.1016/0006-291x(69)90303-9.

Studies on the active center of trypsin. Further characterization of the hydrophobic binding site.

J Biol Chem. 1967 Dec 25;242(23):5777-81.

The interaction of trypsin with neutral substrates and modifiers.

Biochemistry. 1968 Oct;7(10):3616-24. doi: 10.1021/bi00850a039.

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Hydrophobic interactions in the trypsin active center. The sensitivity of the hydrophobic binding site to side chain modifications in competitive inhibitors of the amidinium type.

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Hydrophobic interactions in the trypsin active center. The sensitivity of the hydrophobic binding site to side chain modifications in competitive inhibitors of the amidinium type.

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