左心房感受器在左心房扩张利尿反应中的作用。
The role of left atrial receptors in th diuretic response to left atrial distension.
作者信息
Ledsome J R, Linden R J
出版信息
J Physiol. 1968 Sep;198(2):487-503. doi: 10.1113/jphysiol.1968.sp008619.
Abstract
- The diuretic response to distension of the whole left atrium caused by obstruction of the mitral orifice has been compared with the effects of distension (by means of small balloons) of the left pulmonary vein/left atrial junctions.2. Distension of the pulmonary vein/atrial junctions caused an increase in heart rate and a diuresis similar to but smaller than that caused by mitral obstruction.3. Section of both ansae subclaviae prevented the increase in heart rate produced by distension of the pulmonary vein/left atrial junctions but had little effect on the diuretic response either to pulmonary vein distension or to mitral obstruction.4. A diuretic response to mitral obstruction could be demonstrated after all nerves from the lungs had been cut but not after the vagus nerves had been cut at levels likely to interrupt the majority of afferent fibres from left atrial receptors.5. The results support the view that stimulation of left atrial receptors is a major factor in the production of a diuretic response to mitral obstruction.
摘要
已将二尖瓣口梗阻所致整个左心房扩张引起的利尿反应与左肺静脉/左心房交界处扩张（通过小气球）的效果进行了比较。
肺静脉/心房交界处的扩张引起心率加快和利尿，与二尖瓣梗阻引起的相似但程度较小。
切断双侧锁骨下袢可防止肺静脉/左心房交界处扩张引起的心率加快，但对肺静脉扩张或二尖瓣梗阻引起的利尿反应影响很小。
在切断来自肺部的所有神经后，仍可证明对二尖瓣梗阻有利尿反应，但在可能中断来自左心房感受器的大多数传入纤维的水平切断迷走神经后则无此反应。
这些结果支持这样一种观点，即刺激左心房感受器是对二尖瓣梗阻产生利尿反应的主要因素。
相似文献
1
The role of left atrial receptors in th diuretic response to left atrial distension.左心房感受器在左心房扩张利尿反应中的作用。
J Physiol. 1968 Sep;198(2):487-503. doi: 10.1113/jphysiol.1968.sp008619.
2
The effects of distension of the pulmonary vein-atrial junctions upon peripheral vascular resistance.
J Physiol. 1970 Mar;207(1):1-14. doi: 10.1113/jphysiol.1970.sp009044.
3
The effects of stimulation of left atrial receptors on efferent vagal nerves to the dog heart.刺激犬心脏左心房感受器对迷走神经传出支的影响。
Q J Exp Physiol. 1982 Oct;67(4):595-605. doi: 10.1113/expphysiol.1982.sp002679.
4
Distension of the pulmonary vein - atrial junctions and plasma vasopressin in the chloralose-anaesthetized dog.水合氯醛麻醉犬肺静脉-心房连接处扩张与血浆血管加压素
Can J Physiol Pharmacol. 1983 Aug;61(8):905-10. doi: 10.1139/y83-136.
5
The effect on the efferent vagal nerves to the heart of stimulating atrial receptors in the dog.刺激犬心房感受器对心脏传出迷走神经的影响。
Q J Exp Physiol. 1986 Oct;71(4):549-57. doi: 10.1113/expphysiol.1986.sp003015.
6
The effect of distension of the pulmonary vein-atrial junction on activity of left atrial receptors.肺静脉-心房交界处扩张对左心房感受器活动的影响。
J Physiol. 1978 Dec;285:445-53. doi: 10.1113/jphysiol.1978.sp012581.
7
The nature of the atrial receptors responsible for a reflex decrease in activity in renal nerves in the dog.狗体内负责使肾神经活动反射性降低的心房感受器的性质。
J Physiol. 1980 Mar;300:31-40. doi: 10.1113/jphysiol.1980.sp013149.
8
Humoral nature of the urine response to simulation of atrial receptors.尿液对心房感受器模拟反应的体液性质
Q J Exp Physiol. 1981 Oct;66(4):431-8. doi: 10.1113/expphysiol.1981.sp002585.
9
Reflex effects on the heart of stimulating left atrial receptors.刺激左心房感受器对心脏的反射效应。
J Physiol. 1971 Oct;218(2):447-63. doi: 10.1113/jphysiol.1971.sp009627.
10
The nature of the atrial receptors responsible for a reflex increase in activity in efferent cardiac sympathetic nerves.负责引起心脏传出交感神经活动反射性增加的心房感受器的性质。
Q J Exp Physiol. 1982 Jan;67(1):143-9. doi: 10.1113/expphysiol.1982.sp002608.
引用本文的文献
1
Differential contributions of cardiac, coronary and pulmonary artery vagal mechanoreceptors to reflex control of the circulation.心内、冠状动脉和肺动脉机械感受器对循环反射控制的差异贡献。
J Physiol. 2022 Sep;600(18):4069-4087. doi: 10.1113/JP282305. Epub 2022 Aug 29.
2
The nature of the atrial receptors responsible for a reflex decrease in activity in renal nerves in the dog.狗体内负责使肾神经活动反射性降低的心房感受器的性质。
J Physiol. 1980 Mar;300:31-40. doi: 10.1113/jphysiol.1980.sp013149.
3
Effects of vagotomy on drinking in the rat.迷走神经切断术对大鼠饮水的影响。
J Physiol. 1980 Nov;308:417-26. doi: 10.1113/jphysiol.1980.sp013479.
4
properties of somatosensory cells in the human thalamus.人类丘脑体感细胞的特性
J Physiol. 1971 Jul;216(1):23P-24P.
5
Reflex effects on the heart of stimulating left atrial receptors.刺激左心房感受器对心脏的反射效应。
J Physiol. 1971 Oct;218(2):447-63. doi: 10.1113/jphysiol.1971.sp009627.
6
Nature and location of the receptors for salt-gland secretion in the goose.鹅盐腺分泌受体的性质和位置
J Physiol. 1972 Oct;226(2):453-72. doi: 10.1113/jphysiol.1972.sp009993.
7
The effect on heart rate of distending the atrial appendages in the dog.扩张狗的心耳对心率的影响。
J Physiol. 1972 Sep;225(3):705-19. doi: 10.1113/jphysiol.1972.sp009965.
8
A reflex increase in heart rate from distension of the junction between the superior vena cava and the right atrium.上腔静脉与右心房交界处扩张引起的心率反射性增加。
J Physiol. 1972 Jan;220(1):177-97. doi: 10.1113/jphysiol.1972.sp009700.
9
The binding of tritium-labelled tetrodotoxin to non-myelinated nerve.氚标记的河豚毒素与无髓神经的结合。
J Physiol. 1972 Jul;224(1):25P-26P.
10
Proceedings: Fractionation and assay of chicken porlactin.论文集：鸡催乳素的分级分离与测定
J Physiol. 1974 Apr;238(1):1P-2P.
本文引用的文献
1
The effect of distending a pouch of the left atrium on the heart rate.扩张左心房的一个腔室对心率的影响。
J Physiol. 1967 Nov;193(1):121-9. doi: 10.1113/jphysiol.1967.sp008346.
2
THE DETERMINATION OF SODIUM IN BODY FLUIDS BY THE GLASS ELECTRODE.用玻璃电极测定体液中的钠
J Clin Invest. 1963 Mar;42(3):293-304. doi: 10.1172/JCI104716.
3
The mechanisms by which distension of the left atrium produces diuresis in anaesthetized dogs.在麻醉犬中左心房扩张产生利尿作用的机制。
J Physiol. 1961 Nov;159(1):87-100. doi: 10.1113/jphysiol.1961.sp006794.
4
The anatomy of the autonomic nervous system in the dog.狗的自主神经系统解剖结构。
Am J Anat. 1955 Mar;96(2):285-318. doi: 10.1002/aja.1000960205.
5
CARDIAC RECEPTORS IN THE DOG, WITH PARTICULAR REFERENCE TO TWO TYPES OF AFFERENT ENDING IN THE VENTRICULAR WALL.犬心脏的感受器，特别涉及心室壁中的两种传入末梢类型。
J Physiol. 1964 Nov;174(3):323-39. doi: 10.1113/jphysiol.1964.sp007490.
6
EFFECT OF ACUTE CHANGES IN LEFT ATRIAL PRESSURE ON URINE FLOW IN UNANESTHETIZED DOGS.未麻醉犬左心房压力急性变化对尿流的影响
Am J Physiol. 1964 Sep;207:530-6. doi: 10.1152/ajplegacy.1964.207.3.530.
7
A REFLEX INCREASE IN HEART RATE FROM DISTENSION OF THE PULMONARY-VEIN-ATRIAL JUNCTIONS.肺静脉-心房交界处扩张引起的心率反射性增加。
J Physiol. 1964 Apr;170(3):456-73. doi: 10.1113/jphysiol.1964.sp007343.
8
Circulatory basis of fluid volume control.液体容量控制的循环基础。
Physiol Rev. 1963 Jul;43:423-81. doi: 10.1152/physrev.1963.43.3.423.
9
Electrophysiological evidence of baroreceptors in the pulmonary artery of the dog.犬肺动脉中压力感受器的电生理证据。
J Physiol. 1960 Feb;150(2):319-31. doi: 10.1113/jphysiol.1960.sp006390.
10
The origin and course of the cardioaccelerator fibers in the dog.狗体内心脏加速纤维的起源与走行
Anat Rec. 1958 Nov;132(3):261-79. doi: 10.1002/ar.1091320304.
Zotero 插件