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危地马拉印第安人的迭戈血型遗传学:抗迭戈a和抗迭戈b抗原血清的应用。

Genetics of Diego blood groups in Guatemalan Indians: use of antiserums to Diego a and Diebo b antigens.

作者信息

Cann H M, Van West B, Barnett C R

出版信息

Science. 1968 Dec 20;162(3860):1391-2. doi: 10.1126/science.162.3860.1391.

Abstract

Red blood cells of 255 inhabitants of San Antonio Palopo, an Indian community on the eastern shore of Lake Atitlán, Guatemala, have been typed with antiserum.. to Diego a (Di(a)) and the newly discovered antiserum to Di(b). Individuals with erythrocyte antigenic types Di(a+ b-, Di(a+ b+), and Di(a-b+) have been found, but the type Di(a-b-) has not been encountered. Population frequencies of antigenic types and family studies support the hypothesis that the erythrocyte antigens, Die and Dib, are controlled by two codominant alleles at a single autosomal locus.

摘要

对危地马拉阿蒂特兰湖东岸的一个印第安社区圣安东尼奥-帕洛波的255名居民的红细胞,用抗血清对迭戈a(Di(a))和新发现的抗Di(b)抗血清进行了分型。已发现具有红细胞抗原类型Di(a+b-)、Di(a+b+)和Di(a-b+)的个体,但未遇到Di(a-b-)类型。抗原类型的群体频率和家系研究支持这样的假说,即红细胞抗原Di(a)和Di(b)由常染色体上单一基因座的两个共显性等位基因控制。

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