在诱导增殖的肝脏和肾脏中，刺激的DNA合成与胸苷和胸苷酸激酶活性未改变相关。
Stimulated DNA synthesis in livers and kidneys induced to proliferate associated with unchanged thymidine and thymidylate kinase activities.
作者信息
Cihák A, Seifertová M
出版信息
Chem Biol Interact. 1976 May;13(2):141-9. doi: 10.1016/0009-2797(76)90003-x.
Enhanced mitotic activity and stimulated DNA synthesis associated with unchanged activity of thymidine and thymidylate kinases were observed in mouse kidneys induced to proliferate by intracardiac injection of lead acetate, and in rat livers following repeated administration of 5-azacytidine. On the other hand, the enhanced thymidine kinase activity evoked by L-tryptophan given by intubation at later stages of liver regeneration was paralleled by the enhanced incorporation of thymidine into DNA only to a very small degree.
在心内注射醋酸铅诱导增殖的小鼠肾脏以及反复给予5-氮杂胞苷后的大鼠肝脏中，观察到有丝分裂活性增强和DNA合成受刺激，而胸苷激酶和胸苷酸激酶的活性未改变。另一方面，在肝再生后期经插管给予L-色氨酸所引起的胸苷激酶活性增强，与之平行的是胸苷掺入DNA的增加，但程度非常小。
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