Liubimov B I, Smol'nikova N M, Strekalova S N, Iavorskiĭ A N
Biull Eksp Biol Med. 1979 Feb;87(2):155-8.
In experiments on rats it was shown that carbidine injected intramuscularly for two weeks does not effect gonadotropic action in a dose effective in experimental therapy of alcohol dependence (4 mg/kg). The drug neither potentiates adverse after-effects of chronic action of ethanol on ovo- and spermatogenesis nor slows down the course of the reparative processes in the gonads after ethanol is discontinued. However, further regressive changes in the gonadal generative elements were recorded in administering carbidine against the background of continued use of ethanol.
在对大鼠的实验中发现，以实验性酒精依赖治疗有效剂量（4毫克/千克）肌肉注射卡比啶两周，对促性腺作用无影响。该药物既不增强乙醇对卵子和精子发生的慢性作用的不良后效应，也不减缓乙醇停用后性腺修复过程的进程。然而，在持续使用乙醇的背景下给予卡比啶时，性腺生殖细胞出现了进一步的退行性变化。
