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三尖瓣置换术后严重血管内溶血:采用猪异种移植物置换主动脉瓣和二尖瓣治愈。

Severe intravascular hemolysis after triple valve replacement: cure by replacement of aortic and mitral valves with porcine xenografts.

作者信息

Camishion R C, Hughes J L

出版信息

Surgery. 1979 Mar;85(3):246-8.

PMID:570732
Abstract

A case report of a patient with a triple cardiac valve replacement complicated by severe postoperative intravascular hemolysis is presented. The patient had neither prosthetic valvular dysfunction nor paravalvular leak and had an excellent hemodynamic response to the operation. Despite intensive medical management, the patient required transfusions of 500 ml of blood every 3 weeks. Replacement of the aortic and mitral prostheses with porcine xenografts alleviated the problem. When a patient requires triple valve replacement, the use of homograft or heterograft valves should be seriously considered as a means of minimizing this potential complication.

摘要

本文报告了一例接受三尖瓣置换术后并发严重血管内溶血的病例。该患者既没有人工瓣膜功能障碍,也没有瓣周漏,并且手术的血流动力学反应良好。尽管进行了强化药物治疗,但患者仍需要每3周输注500毫升血液。用猪异种移植物替换主动脉瓣和二尖瓣假体缓解了这一问题。当患者需要进行三尖瓣置换时,应认真考虑使用同种异体移植物或异种移植物瓣膜,以尽量减少这种潜在并发症。

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1
Severe intravascular hemolysis after triple valve replacement: cure by replacement of aortic and mitral valves with porcine xenografts.三尖瓣置换术后严重血管内溶血:采用猪异种移植物置换主动脉瓣和二尖瓣治愈。
Surgery. 1979 Mar;85(3):246-8.
2
Hemolytic anemia associated with heterograft replacement of the mitral valve.与二尖瓣异种移植置换相关的溶血性贫血。
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[Intravascular hemolysis after multiple valvular replacement procedures--a case report].[多次瓣膜置换术后的血管内溶血——一例报告]
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