时间遗传学和双胞胎学在预防遗传疾病中的作用。
The role of chronogenetics and of gemellology in the prevention of genetic morbidity.
作者信息
Gedda L
出版信息
Acta Genet Med Gemellol (Roma). 1978;27:5-10. doi: 10.1017/s0001566000009454.
PMID:571658
Abstract
The prevention of hereditary diseases after birth is essentially based on the detection of these diseases at their preclinical level. This may be made possible through a careful pedigree examination and possible identification of a "genealogical alarm", as well as a detailed clinical examination of the subject and possible identification of preclinical signs of the pathogenesis, i.e., of a "clinical alarm". The respective roles of chronogenetics and of gemellology in this approach are reviewed.
摘要
出生后遗传性疾病的预防主要基于在临床前阶段对这些疾病的检测。这可以通过仔细的家系检查并可能识别出“系谱警报”，以及对个体进行详细的临床检查并可能识别出发病机制的临床前体征，即“临床警报”来实现。本文综述了时间遗传学和双胎学在这种方法中的各自作用。
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