Matz D, Enders P, Baumeister G
J Neurol. 1976 Apr 23;212(2):177-82. doi: 10.1007/BF00329161.
A case of a patient with hyperinsulinism due to insulinoma associated with neurological and psychiatric disturbances including EEG alterations is reported. The hunger test as well as the i.v. tolbutamid test proved to be of diagnostic importance. In addition, the electroencephalographic studies combined with blood sugar analyses before and after 50 g glucose, orally, showed a reversibility of the EEG alterations together with normalization of the blood surgar levels. These results point to the possibility of differentiating biochemical from structural cerebral lesions associated with hyperinsulinism.
报告了一例因胰岛素瘤导致高胰岛素血症并伴有包括脑电图改变在内的神经和精神障碍的患者。饥饿试验以及静脉注射甲苯磺丁脲试验被证明具有诊断意义。此外，脑电图研究结合口服50克葡萄糖前后的血糖分析显示，脑电图改变具有可逆性，同时血糖水平恢复正常。这些结果表明，有可能区分与高胰岛素血症相关的生化性脑损伤和结构性脑损伤。
