Effects of hydroxyurea on DNA and RNA synthesis in mouse skin, liver, and thymus and on skin tumorigenesis initiated by beta-propiolactone.
作者信息
Smith H C, Boutwell R K, Potter V R
出版信息
Cancer Res. 1968 Nov;28(11):2217-27.
PMID:5723966
Abstract
摘要
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Hydroxyurea: possible relationship of cytotoxicity to inhibition of skin carcinogenesis.羟基脲：细胞毒性与皮肤癌发生抑制之间的可能关系。
J Natl Cancer Inst. 1971 Apr;46(4):841-4.
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Effect of hydroxyurea and cytarabine on rodent epidermal cells.羟基脲和阿糖胞苷对啮齿动物表皮细胞的作用。
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The in vivo binding of beta-propiolactone to mouse skin DNA, RNA, and protein.β-丙内酯与小鼠皮肤DNA、RNA和蛋白质的体内结合
Cancer Res. 1968 Apr;28(4):642-52.
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Isotope-dilution studies of the effects of 5-fluorodeoxyuridine and hydroxyurea on the incorporation of deoxycytidine and thymidine by cultured thymus cells.5-氟脱氧尿苷和羟基脲对培养胸腺细胞中脱氧胞苷和胸苷掺入影响的同位素稀释研究。
Can J Biochem. 1976 Mar;54(3):238-48. doi: 10.1139/o76-037.
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Hydroxyurea exposure triggers tissue-specific activation of p38 mitogen-activated protein kinase signaling and the DNA damage response in organogenesis-stage mouse embryos.羟脲暴露在器官发生阶段的小鼠胚胎中引发组织特异性的 p38 丝裂原活化蛋白激酶信号转导和 DNA 损伤反应。
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