Gold E B, Gordis L
Ann Neurol. 1979 Jun;5(6):565-8. doi: 10.1002/ana.410050612.
A population-based community-wide study of the incidence of brain tumors in children from 1960 through 1974 was conducted in the Baltimore area. Incidence rates in boys declined from 1960 to 1974 and were higher in whites than in blacks in all age groups except children under 5 years. A peak in incidence rates was observed in white 5- to 9-year-olds and in blacks from 0 to 4 years of age. In addition, incidence rates tended to be higher in boys than in girls at all ages except at puberty-the 10- to 14-year-old age group-when rates in girls exceeded those in boys. The findings suggest that both host and environmental factors may be involved in the cause of brain tumors in children.
在巴尔的摩地区开展了一项基于人群的全社区研究,以调查1960年至1974年期间儿童脑肿瘤的发病率。1960年至1974年期间,男孩的发病率有所下降,除5岁以下儿童外,所有年龄组白人的发病率均高于黑人。在5至9岁的白人儿童以及0至4岁的黑人儿童中观察到发病率出现峰值。此外,除了青春期(10至14岁年龄组)女孩发病率超过男孩外,其他各年龄段男孩的发病率往往高于女孩。这些研究结果表明,宿主因素和环境因素可能都与儿童脑肿瘤的病因有关。