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放射疗法治疗人类同种异体肾移植急性排斥反应

Radiotherapy in treatment of acute rejection of human renal allografts.

作者信息

Godfrey A M, Salaman J R

出版信息

Lancet. 1976 May 1;1(7966):938-9. doi: 10.1016/s0140-6736(76)92715-x.

Abstract

36 patients who received a renal transplant and who subsequently underwent a rejection episode were randomised into two groups. The first group received a standard form of rejection therapy consisting in high doses of steroid drugs, and the second group received in addition 600 rads of radiotherapy to the graft. After three years (minimum follow-up twelve months) the groups were compared with respect to patient and graft survival and level of transplant function. No benefit was obtained by the group receiving radiotherapy.

摘要

36名接受肾移植且随后经历排斥反应的患者被随机分为两组。第一组接受由高剂量类固醇药物组成的标准排斥治疗形式,第二组除接受标准治疗外还对移植肾给予600拉德的放射治疗。三年后(最短随访十二个月),对两组患者的生存率、移植肾存活率及移植肾功能水平进行比较。接受放射治疗的组未获得益处。

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