Rep B H, Bos R
Tijdschr Diergeneeskd. 1979 Oct 1;104(19):747-58.
A series of experimental infections in a total number of twenty-two dogs showed that transmission of the parasite Uncinaria stenocephala from one dog to another is readily achieved by oral route. Cutaneous infection was only successful when large doses were used. From the topographical distribution of some intestinal U. stenocephala worm populations in dogs it was concluded that the hookworm population is concentrated in the proximal part of the ileum. The expulsion of worms observed may be evidence of the size or persistence of the worm population. The prepatent period was found to be (at least) thirteen days, both in dogs and in foxes. Daily worm-egg counts showed a fluctuating rhythm, particularly during the first 2-3 weeks of the patent period. Relatively high peaks were also recorded in some cases. The maximum number of worms eggs was estimated at well over 5,000 eggs per female U. stenocephala worm (in dogs). U. stenocephala eggs and larvae are capable of surviving at low temperatures. U. stenocephala infection was found to be present in twenty-five (86 per cent) out of twenty-nine foxes obtained and examined in 1975, the worm load varying from one to 176 hookworms and averaging thirty worms per fox. From the preliminary results of a number of experimental transmissions it was concluded that foxes and dogs harbour adapted strains of U. stenocephala, which prevents cross infections between these reservoirs from occurring to more than a limited extent.
对总共22只狗进行的一系列实验性感染表明，狭头钩虫可通过口服途径轻易地在狗之间传播。只有使用大剂量时，皮肤感染才会成功。根据狗肠道内某些狭头钩虫种群的分布情况得出结论，钩虫种群集中在回肠近端。观察到的驱虫现象可能证明了蠕虫种群的规模或持续性。在狗和狐狸身上发现，潜伏期（至少）为13天。每日虫卵计数显示出波动的节律，尤其是在感染期的前2至3周。在某些情况下还记录到了相对较高的峰值。估计每只雌性狭头钩虫（在狗身上）的虫卵最大数量超过5000个。狭头钩虫的虫卵和幼虫能够在低温下存活。在1975年获取并检查的29只狐狸中，发现有25只（86%）感染了狭头钩虫，蠕虫数量从1条到176条不等，每只狐狸平均有30条。根据一些实验性传播的初步结果得出结论，狐狸和狗体内携带适应的狭头钩虫菌株，这使得这些宿主之间的交叉感染仅在有限程度上发生。
