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实验性应激下心血管功能稳定性不同的大鼠胃肾上腺素能神经支配的功能状态

Functional state of adrenergic innervation of the stomach in rats with different stability of cardiovascular functions in experimental stress.

作者信息

Krokhina E M, Scotselyas Y G, Yumatov E A

出版信息

Ann Anat Pathol (Paris). 1979;24(1):3-14.

PMID:573976
Abstract

Stress is induced in male Wistar and August rats by immobilising them for 30 hours. Nerve endings were studied using the method of fluorescent microscopy of Falck and Owman, modified by E. M. Krokhina. These studies showed that the dystrophic process related to stress acts on the activation system of the adrenergic innervation. This activation of transmitter synthesis in all the neurones is related to the large number of adrenergic transmitter substances found in the stomach wall. There are differences between animal species: August rats are more sensitive. This no doubt reflects a general instability in the vegetative functions of this species. The authors conclude that depending on the animal species there are factors in the stomach which may either afford resistance or predispose the organism to disorders of the cardiovascular system.

摘要

通过将雄性Wistar大鼠和奥古斯特大鼠固定30小时来诱导应激。采用经E.M.克罗希娜改良的法尔克和欧文曼荧光显微镜法对神经末梢进行研究。这些研究表明,与应激相关的营养不良过程作用于肾上腺素能神经支配的激活系统。所有神经元中递质合成的这种激活与在胃壁中发现的大量肾上腺素能递质物质有关。动物物种之间存在差异:奥古斯特大鼠更敏感。这无疑反映了该物种植物性功能的普遍不稳定性。作者得出结论,取决于动物物种,胃中存在的因素可能要么提供抵抗力,要么使机体易患心血管系统疾病。

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