磷酸肌酸对心脏乳酸脱氢酶和肌肉丙酮酸激酶的抑制作用是由一种污染物导致的。
Creatine phosphate inhibition of heart lactate dehydrogenase and muscle pyruvate kinase is due to a contaminant.
作者信息
Tornheim K, Lowenstein J M
出版信息
J Biol Chem. 1979 Nov 10;254(21):10586-7.
PMID:574139
Abstract
Previously reported inhibitions of heart lactate dehydrogenase (Guppy, M., and Hochachka, P.W. (1978) J. Biol. Chem. 253, 8465-8469) and muscle pyruvate kinase (Kemp, R.G. (1973) J. Biol. Chem. 248, 3963-3967) by creatine phosphate are due to oxalate which is a contaminant found in some commercial preparations of creatine phosphate.
摘要
先前报道的磷酸肌酸对心脏乳酸脱氢酶的抑制作用（Guppy, M., 和 Hochachka, P.W. (1978) 《生物化学杂志》253, 8465 - 8469）以及对肌肉丙酮酸激酶的抑制作用（Kemp, R.G. (1973) 《生物化学杂志》248, 3963 - 3967）是由于草酸盐引起的，草酸盐是在一些商业磷酸肌酸制剂中发现的污染物。
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