酒精中毒对白鼠腹腔巨噬细胞吞噬活性的影响
[Changes in the phagocytic activity of the peritoneal macrophages of white mice caused by alcoholic intoxication].
作者信息
Fomina V G, Evseev V A
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1979 Oct(10):100-3.
PMID:574347
Abstract
Observations made on white mice showed that doses of alcohol had a stimulating effect on the indices of macrophage acitivity (pagocytic number and phagocytic index), while longer administration of 40% ethyl alcohol solution (in doses of 0,1 ml for 21--30 days) suppressed the functional activity of macrophages. In vitro experiments in which macrophages were subjected to the action of ethyl alcohol showed that alcohol, depending on its concentration, had a direct effect on the cells of the microphage system.
摘要
对白鼠的观察表明，一定剂量的酒精对巨噬细胞活性指标（吞噬数量和吞噬指数）有刺激作用，而长期给予40%乙醇溶液（剂量为0.1毫升，持续21 - 30天）会抑制巨噬细胞的功能活性。在体外实验中，让巨噬细胞受到乙醇作用，结果显示酒精根据其浓度不同，对巨噬细胞系统的细胞有直接影响。
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