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大鼠卵巢中NADPH δ4-3-酮类固醇-5α-氧化还原酶的定位

Localisation of the NADPH delta 4-3-keto steroid-5 alpha-oxidoreductase in the rat ovary.

作者信息

Koninckx P R, De Moor P

出版信息

Ann Endocrinol (Paris). 1979;40(5):513-4.

PMID:574748
Abstract

The 5 alpha-reductase activity was localised on the stromal comportment of the rat ovary. The 5 alpha-reductase activity in stromal tissue decreased from 27.3 +/- 2.9 ng/hr/mg protein in rats 20 days old, to 13.4 +/- 1.2 ng/hr/mg protein in rats 30 days old and to 7.1 +/- 1.0 ng/hr/mg protein in adult rats. During the oestrous cycle no significant variations in enzyme activity could be demonstrated.

摘要

5α-还原酶活性定位于大鼠卵巢的基质部分。基质组织中的5α-还原酶活性在20日龄大鼠中为27.3±2.9纳克/小时/毫克蛋白质,在30日龄大鼠中降至13.4±1.2纳克/小时/毫克蛋白质,在成年大鼠中为7.1±1.0纳克/小时/毫克蛋白质。在发情周期中,未发现酶活性有显著变化。

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