Meerson F Z, Malyshev V V, Popova N S, Markovskaia G I
Biull Eksp Biol Med. 1979 Dec;88(12):659-61.
The effect of preliminary Na gamma-hydroxybutyric acid (GHBA) injection on the activation of adrenergic and hypophyseal-adrenal systems during emotional-painful stress and ulcerous affection of the stomach after the stress cessation was studied in experiments on rats. It was established that the preliminary GHBA administration inhibits stimulation of stress causing systems and thereby prevents ulcerous affection of the stomach mucosa. It is suggested that the activation of GHBA-ergic inhibiting system, which accompanies the stress, is a natural mechanism of limitation of the stress reaction and prevention of the stress affections.
在大鼠实验中，研究了预先注射γ-羟基丁酸（GHBA）对情绪性疼痛应激期间肾上腺素能和垂体-肾上腺系统激活以及应激停止后胃溃疡性病变的影响。结果表明，预先给予GHBA可抑制应激引发系统的刺激，从而预防胃黏膜的溃疡性病变。有人认为，应激时伴随的GHBA能抑制系统的激活是限制应激反应和预防应激性病变的一种自然机制。
