Bianucci P, Pastorino G, De Rossi O, Brondi P
Minerva Med. 1979 Dec 1;70(54):3701-4.
110 patients observed over a three-year period suffering from cancer of the breast, digestive apparatus, lung and urogenital apparatus, and submitted simultaneouly to the DNCB skin test and to radioimmunological measurement of CEA have been studied. Confirming what has already been reported, the epicutaneous findings and laboratory results show there is an almost constant correlation between marked reactivity to DNCB and normal CEA titre and that, on the contrary, ml response to immune stimulation is often matched by a pathological CEA value. It is maintained that this type of cross investigation may be important for prognosis as the basis for initial assessment of the probable clinical course of the disease and the response of the patient to immunochemotherapeutic treatment.
对110例在三年期间患有乳腺癌、消化器官癌、肺癌和泌尿生殖器官癌的患者进行了研究，这些患者同时接受了二硝基氯苯（DNCB）皮肤试验和癌胚抗原（CEA）的放射免疫测定。正如已经报道的那样，表皮试验结果和实验室结果证实，对DNCB的明显反应性与正常CEA滴度之间几乎始终存在相关性，相反，免疫刺激的微弱反应往往与CEA的病理值相匹配。有人认为，这种交叉研究对于预后可能很重要，可作为对疾病可能的临床病程以及患者对免疫化疗治疗反应进行初步评估的基础。
