Krunajević T, Bergsten G
Acta Vet Scand. 1968;9(2):112-5. doi: 10.1186/BF03547877.
The clinical and pathological details of a case of ataxia in a 3-month-old colt are described. A marked protrusion into the vertebral canal of the body of the 3rd cervical vertebra was observed. C and C were immovably joined so that the deformity could not be corrected by extension of the spinal column at this point. There was a compression of the spinal cord corresponding to the protrusion. The cause of this luxation could not be established. It may be assumed that the distortion was congenital, or caused by trauma at an early stage and that clinical symptoms could be observed only when, a marked narrowing of the vertebral canal had arisen as a result of the growth of the sceleton. Histopathological examination of the spinal cord at the site of the compression revealed severe malacia with marked gliosis and perivascular fibrosis involving dorsal, lateral and ventral white funiculi and gray matter. Secondary changes were observed ahead of and behind the primary lesion. Distribution and extent of the lesions are shown graphically. In principle, clinical manifestation and pathological findings seem to be very similar to those which are observed in the disease described in the USA and other countries as “wobbles”.
描述了一匹3个月大小马共济失调病例的临床和病理细节。观察到第三颈椎椎体明显突入椎管。第三颈椎和第四颈椎牢固连接,因此此时脊柱伸展无法纠正畸形。脊髓在相应突出部位受到压迫。这种脱位的原因无法确定。可以推测这种变形是先天性的,或者是早期创伤所致,并且只有当骨骼生长导致椎管明显变窄时才会出现临床症状。对受压部位脊髓的组织病理学检查显示严重软化,伴有明显的胶质细胞增生和血管周围纤维化,累及背侧、外侧和腹侧白质束以及灰质。在原发性病变的前方和后方观察到继发性变化。病变的分布和范围以图表形式展示。原则上,临床表现和病理结果似乎与在美国和其他国家描述为“摇摆病”的疾病中观察到的非常相似。