Meyer-Breiting E, von Ilberg C
ORL J Otorhinolaryngol Relat Spec. 1979;41(5):288-300. doi: 10.1159/000275447.
A report is given of the follow-up and behavior of 149 supraglottic squamous carcinomas treated by combined radiosurgical therapy. In 27 cases supraglottic laryngectomy and in 4 cases epiglottectomy was performed. The other cases underwent laryngectomy. The 3-year survival rate was 60% and the 5-year survival rate 51.2%. 64% of the patients without nodular metastases and 45% of the patients with histologically ascertained nodular metastases and 45% of the patients with histologically ascertained nodular metastases survived the 3-year interval. The main localizations of the supraglottic tumors are compared with the tendency to spread into unilateral, homolateral, contralateral or bilateral sites, respectively. A comparative study by serial sectioning of 51 supraglottic squamous carcinomas shows that the tendency to nodular metastases increases with decreasing differentiation of the tumor.
本文报告了149例接受放射外科联合治疗的声门上型鳞状细胞癌的随访情况及行为。其中27例行声门上喉切除术，4例行会厌切除术，其他病例行喉切除术。3年生存率为60%，5年生存率为51.2%。无结节性转移的患者中64%、经组织学确诊有结节性转移的患者中45%存活超过3年。比较了声门上肿瘤的主要部位分别向单侧、同侧、对侧或双侧扩散的倾向。对51例声门上型鳞状细胞癌进行连续切片的对比研究表明，肿瘤分化程度越低，发生结节性转移的倾向越高。
