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血小板减少性紫癜中血小板相关IgG的定量分析(作者译)

[Quantification of platelet associated IgG in thrombocytopenic purpura (authors transl)].

作者信息

Boizard B, Wautier J L, Caen J

出版信息

Presse Med (1893). 1979 Dec 10;8(48):3943-6.

PMID:575215
Abstract

One hundred and twenty four tests of quantification of platelet associated IgG were done in patients with thrombocytopenia. The level was increased in 80% of the patients with ITP. The platelet associated IgG level does not seem a prognosis tool but is useful to follow the evolution. Platelet associated IgG levels higher than 600 x 10(-16) g/platelet were only observed in ITP (control less than 54 x 10(-16) g/platelet). Level lower than 600 x 10(-16) g/platelet were observed in systemic lupus erythematosus, chronic lymphocytic leukemia or chronic hepatitis. In defective thrombopoïesis, the levels were always normal.

摘要

对血小板减少症患者进行了124次血小板相关IgG定量检测。80%的免疫性血小板减少症(ITP)患者该水平升高。血小板相关IgG水平似乎不是一种预后工具,但对跟踪病情进展有用。仅在ITP患者中观察到血小板相关IgG水平高于600×10⁻¹⁶ g/血小板(对照组低于54×10⁻¹⁶ g/血小板)。在系统性红斑狼疮、慢性淋巴细胞白血病或慢性肝炎患者中观察到水平低于600×10⁻¹⁶ g/血小板。在血小板生成缺陷中,该水平始终正常。

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