糖尿病患者心肌中三磷酸腺苷（ATP）和磷酸肌酸减少：2,3-二磷酸甘油酸的作用
Reduced myocardial ATP and creatine phosphate in diabetes: role of 2,3-diphosphoglycerate.
作者信息
Allison T B, Shipp J C, Bruttig S P, Eliot R S
出版信息
Recent Adv Stud Cardiac Struct Metab. 1975;7:193-7.
PMID:5754
Abstract
Observations are presented which suggest that myocardial cellular hypoxia may account for the reduction in myocardial ATP and CP in the ketoacidotic diabetic state. It is suggested that reduced 2,3-diphosphoglycerate adversely affects oxygen release from the red blood cell, thereby leading to myocardial cellular hypoxia.
摘要
所呈现的观察结果表明，心肌细胞缺氧可能是酮症酸中毒糖尿病状态下心肌三磷酸腺苷（ATP）和磷酸肌酸（CP）减少的原因。有人提出，2,3 - 二磷酸甘油酸减少会对红细胞的氧释放产生不利影响，从而导致心肌细胞缺氧。
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