Bickmore J T, Marshall M L
Laryngoscope. 1976 Apr;86(4):516-23. doi: 10.1288/00005537-197604000-00007.
Nasal cytograms, as an aid to diagnosis of pathological conditions of the nose and paranasal sinuses, have not been adopted by the majority of otolaryngologists. This situation exists because of technical problems with the preparation of a slide and the difficulty in finding someone competent and interested in its interpretation. The work of the Bryans has provided an analysis of the cytology of nasal secretions. Adopting their methods, we have been using the nasal cytogram in clinical practice and find it helpful in determining appropriate therapy for problems encountered in otolaryngological practice. In the authors' experience, profuse nasal mastocytosis is a consistent finding in cytograms from patients having varied symptoms that are associated with hypersensitivities that are not accompanied by positive objective findings. This is especially true in patients with constantly recurring headaches and those with a chronically obstructed nose. Once many mast cells are found by the cytogram, attempts are made to relieve these patients by selective dietary restrictions. These attempts are often successful. The nasal cytogram is also used to help explain periodic symptom flares in the long term allergy patient undergoing immunotherapy for inhalants, by identifying superimposed viral and bacterial infections.
鼻细胞学涂片作为辅助诊断鼻及鼻窦病理状况的手段，尚未被大多数耳鼻喉科医生采用。出现这种情况是因为制作涂片存在技术问题，且难以找到有能力且有兴趣解读涂片的人。布莱恩斯的研究对鼻分泌物的细胞学进行了分析。采用他们的方法，我们一直在临床实践中使用鼻细胞学涂片，发现它有助于为耳鼻喉科实践中遇到的问题确定合适的治疗方法。根据作者的经验，在有各种与过敏相关症状但无阳性客观体征的患者的细胞学涂片中，大量鼻肥大细胞增多是一个常见发现。这在经常反复头痛的患者和长期鼻塞的患者中尤为明显。一旦通过细胞学涂片发现大量肥大细胞，就尝试通过选择性饮食限制来缓解这些患者的症状。这些尝试往往是成功的。鼻细胞学涂片还可用于通过识别叠加的病毒和细菌感染，帮助解释接受吸入性过敏原免疫治疗的长期过敏患者的周期性症状发作。
