对单剂量犬钩虫幼虫实验感染小鼠肠道中组胺的药理学评估。

Pharmacological estimation of histamine in the intestine of mice experimentally infected with single doses of Ancylostoma caninum larvae.

作者信息

Vardhani V, Johri G N

出版信息

J Hyg Epidemiol Microbiol Immunol. 1979;23(4):452-6.

Abstract

Histamine content of the intestine of young female Swiss albino mice experimentally infected per os with low (500) and high (2000) doses of Ancylostoma caninum larvae was studied. The histamine level increased in both the experimental groups reaching peak values on the 16th day post infection in animals inoculated with a dose of 500 larvae and on the 30th day post infection in animals inoculated with 2000 larvae; the histamine content was 2.5 times higher in the former and 4 times higher in the latter than that in the uninfected controls.

摘要

研究了经口实验性感染低剂量（500条）和高剂量（2000条）犬钩虫幼虫的幼年雌性瑞士白化小鼠肠道中的组胺含量。两个实验组的组胺水平均升高，接种500条幼虫的动物在感染后第16天达到峰值，接种2000条幼虫的动物在感染后第30天达到峰值；前者的组胺含量比未感染对照组高2.5倍，后者比未感染对照组高4倍。

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Pharmacological estimation of histamine in the intestine of mice experimentally infected with single doses of Ancylostoma caninum larvae.对单剂量犬钩虫幼虫实验感染小鼠肠道中组胺的药理学评估。

J Hyg Epidemiol Microbiol Immunol. 1979;23(4):452-6.

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