Blum M, Kirsten M, Worth M H
JAMA. 1977 Jan 17;237(3):262-3. doi: 10.1001/jama.237.3.262.
Reversible hypertension occurred in a patient during episodes of hypercalcemia caused by hyperparathyroidism, vitamin D toxicity, and an infusion of calcium during an 11-year period of observation. It is suggested that normal renal function may be required for the hypertension of hyperparathyroidism to be reversible and that the hypertension may be directly related to the hypercalcemia in some patients. Early surgery is suggested for otherwise asymptomatic, mildly hypercalcemia hyperparathyroidism that is accompanied by hypertension.
在11年的观察期内,一名患者在甲状旁腺功能亢进、维生素D中毒以及输注钙导致高钙血症发作期间出现了可逆性高血压。有人认为,甲状旁腺功能亢进引起的高血压若要可逆,可能需要正常的肾功能,而且在某些患者中,高血压可能与高钙血症直接相关。对于无症状的轻度高钙血症甲状旁腺功能亢进且伴有高血压的患者,建议早期手术治疗。