Wilson J, Turner D J
Br Med J. 1969 Feb 1;1(5639):280-3. doi: 10.1136/bmj.1.5639.280.
Investigation of a series of 150 obstetric patients, the majority undergoing caesarean section, showed the expected figure of 2% with factual recall. There was, however, a 17.3% occurrence of unpleasant recall-associated in 10 cases (6.6% of the total) with recall of pain. There was a negative correlation between the giving of a narcotic within six hours of the operation and the occurrence of unpleasant recall. Several other aetiological factors-age, parity, preoperative emotional tension, ventilation, nitrous oxide wash-out with oxygen, and nitrous oxide concentration-were investigated and no relation was found between them and unpleasant recall. It is suggested, therefore, that premedication still has an important function in light anaesthesia, using muscle relaxants, to prevent any form of unpleasant operative awareness.
对150例产科患者进行的系列调查显示,大多数患者接受剖宫产手术,实际回忆率为预期的2%。然而,在10例(占总数的6.6%)有疼痛回忆的病例中,不愉快回忆相关发生率为17.3%。手术6小时内使用麻醉剂与不愉快回忆的发生呈负相关。还对其他几个病因因素进行了研究,包括年龄、产次、术前情绪紧张、通气、用氧气排出一氧化二氮以及一氧化二氮浓度,但未发现它们与不愉快回忆之间存在关联。因此,有人提出,在使用肌肉松弛剂的浅麻醉中,术前用药对于预防任何形式的不愉快术中知晓仍具有重要作用。