脱氧胞苷与辐射反应：人肝脏中极高的脱氧胞苷氨基水解酶活性
Deoxycytidine and radiation response: exceedingly high deoxycytidine aminohydrolase activity in human liver.
作者信息
Zícha B, Buric L
出版信息
Science. 1969 Jan 10;163(3863):191-2. doi: 10.1126/science.163.3863.191.
PMID:5762767
Abstract
The activity of deoxycytidine aminohydrolase in the liver of various species including man was investigated. An enormously high activity was found in human liver. This fact explains the extraordinarily low level of deoxycytidine in human urine in comparison with that of other tested species. The suitability of deoxycitidinuria as a biochemical indicator of postirradiation damage in man remains, therefore, an open question.
摘要
对包括人类在内的各种物种肝脏中的脱氧胞苷氨基水解酶活性进行了研究。发现人类肝脏中该酶活性极高。这一事实解释了与其他受试物种相比，人类尿液中脱氧胞苷水平极低的现象。因此，脱氧胞苷尿作为人类辐射后损伤生化指标的适用性仍是一个悬而未决的问题。
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