Saruk M, Eisenstein R
Arch Pathol Lab Med. 1977 Feb;101(2):74-7.
Areas of medial alteration (Erdheim cystic medionecrosis) in an aortic root aneurysm surgically removed from a patient with Marfan syndrome were studied with an electron microscope. The single striking morphologic abnormality was the disorganized, haphazard architecture of the media in these areas. This lesion is interpreted as being an abortive reparative response to hemodynamic stress in a condition with a molecular defect in the structural proteins of connective tissue.
对一名患有马凡综合征的患者手术切除的主动脉根部动脉瘤中内侧改变区域（厄尔德海姆囊性中膜坏死）进行了电子显微镜研究。唯一显著的形态学异常是这些区域中膜结构紊乱、杂乱无章。这种病变被解释为在结缔组织结构蛋白存在分子缺陷的情况下，对血流动力学应激的一种失败的修复反应。
