Toyoshima K, Matsumoto Y, Nishida M, Yabuuchi H
Acta Endocrinol (Copenh). 1977 Mar;84(3):527-37. doi: 10.1530/acta.0.0840527.
Five cases, 2 males and 3 females, with absence of iodide concentrating mechanism are reported. Three of the five subjects are siblings and the eldest sister has no symptom to account for the cretinism. All 5 cases have improved clinically following the administration of potassium iodide and 4 cases are still in a euthyroid state without any adverse effects during a half to more than 4 years. This study suggests that the absence of iodide concentrating mechanism might be erroneously diagnosed as athyroidal cretinism or adolescent non-toxic diffuse goitre, and may at times not show any clinical symptoms.
本文报告了5例无碘浓缩机制的患者，其中男性2例，女性3例。5例患者中有3例为兄弟姐妹，大姐无克汀病症状。所有5例患者在服用碘化钾后临床症状均有改善，4例患者在半年至4年多的时间里仍处于甲状腺功能正常状态，且无任何不良反应。本研究表明，无碘浓缩机制可能被误诊为甲状腺性克汀病或青少年非毒性弥漫性甲状腺肿，且有时可能不表现出任何临床症状。
