Olsson C A, Deckers P J, Williams L, Mozden P J
Urology. 1976 Apr;7(4):355-61. doi: 10.1016/0090-4295(76)90245-4.
Our experience with 18 patients undergoing pelvic exenteration for advanced primary or recurrent pelvic malignancies is presented. Only one postoperative death was noted, and morbidity was minimal despite the advanced age and high incidence of radiotherapy failures seen in our patients. Although no improvement in cure of malignancy has been seen in this small series, appreciable periods of symptom-free life have been achieved in patients who were previously incapacitated by extensive pelvic pain, fistulas, sepsis, hemorrhage and urinary-fecal incontinence. Because of the symptomatic palliation obtained in our experience, with minimal morbidity and mortality, we have developed a liberal attitude toward the use of pelvic exenteration in the management of selected patients with extensive pelvic malignancy, even when cure is not anticipated.
本文介绍了我们对18例因晚期原发性或复发性盆腔恶性肿瘤而接受盆腔脏器清除术患者的治疗经验。仅记录到1例术后死亡，尽管患者年龄较大且放疗失败发生率较高，但并发症发生率极低。虽然在这个小样本系列中未观察到恶性肿瘤治愈率的提高，但对于那些先前因广泛盆腔疼痛、瘘管、败血症、出血和大小便失禁而丧失活动能力的患者，已实现了相当长一段时间的无症状生存期。鉴于我们的经验显示该手术能缓解症状，且发病率和死亡率极低，我们对在选定的广泛盆腔恶性肿瘤患者管理中使用盆腔脏器清除术持较为宽松的态度，即使预计无法治愈。
