Paradelis A G, Triantaphyllidis C, Markomichelakis J M, Logaras G
Arzneimittelforschung. 1977;27(1):141-3.
Aminodeoxykanamycin (Kaneudomycin) as well as other members of the aminoglycoside antibiotics, has an action at the neuromuscular junction. Kanendomycin was found to be five times less potent than gentamycin, as far as their neuromuscular blocking action on the rat diaphragm is concerned. The neuromuscular blocking action on the rat diaphragm is concerned. The neuromuscular blockade produced by Kanendomycin is not reversed by neostigmine but only by calcium chloride.
氨基脱氧卡那霉素(卡那优霉素)以及其他氨基糖苷类抗生素成员,在神经肌肉接头处有作用。就对大鼠膈肌的神经肌肉阻断作用而言,发现卡那霉素的效力比庆大霉素低五倍。其涉及对大鼠膈肌的神经肌肉阻断作用。卡那霉素产生的神经肌肉阻断作用不能被新斯的明逆转,而只能被氯化钙逆转。