Pemberton L B
JAMA. 1977 Jun 6;237(23):2511-3.
Fulminant pulmonary edema developed in two young, healthy adults within one hour after blood loss, hypolemic shock, and an anaphylactoid reaction to intravenous pyelogram dye. Pulmonary edema developed and they subsequently passed large amounts of edema fluid through the endotracheal tube. Massive loss of plasma-like fluid from the lung required frequent evacuation of the endotracheal tube and intravenous replacement with large amounts of albumin-containing fluids. Both patients were treated with a volume respirator, positive end-expiratory pressure, 100% oxygen, corticosteroids, and tracheostomy. Both patients recovered from massive pulmonary edema with very severe hypoxemia and, three months afterwards, had normal pulmonary function, blood gas levels, and no evidence of pulmonary injury.
两名年轻健康的成年人在失血、低血容量性休克以及对静脉肾盂造影染料发生类过敏反应后一小时内出现暴发性肺水肿。肺水肿发生后，他们随后通过气管内导管排出了大量水肿液。肺部大量血浆样液体流失，需要频繁清理气管内导管，并静脉输注大量含白蛋白的液体进行补充。两名患者均接受了容量型呼吸机、呼气末正压通气、100%氧气、皮质类固醇和气管切开术治疗。两名患者均从伴有非常严重低氧血症的大量肺水肿中康复，三个月后，肺功能、血气水平正常，且无肺损伤迹象。
