间歇性美索比妥用于保守牙科治疗的生理反应
Physiological responses to intermittent methohexitone for conservative dentistry.
作者信息
Wise C C, Robinson J S, Heath M J, Tomlin P J
出版信息
Br Med J. 1969 May 31;2(5656):540-3. doi: 10.1136/bmj.2.5656.540.
Abstract
Intermittent methohexitone for conservative dentistry has been shown to cause clinically undetectable respiratory obstruction, depression of the laryngeal reflex, and arterial hypoxaemia. Because of the pronounced decrease in total peripheral resistance, the blood pressure was maintained only by large increases in cardiac output. Furthermore, the output of the heart could not increase when challenged by hypoxia.
摘要
间歇性使用美索比妥进行保守牙科治疗已被证明会导致临床上难以察觉的呼吸阻塞、喉反射抑制和动脉血氧不足。由于总外周阻力显著降低，仅通过大幅增加心输出量来维持血压。此外，当受到低氧挑战时，心脏的输出量无法增加。
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