与非霍奇金淋巴瘤相关的 florid 上皮样细胞和结节病样反应

Florid epithelioid cell and sarcoid-type reaction associated with non-Hodgkin's lymphoma.

作者信息

Kahn L B, King H, Jacobs P

出版信息

S Afr Med J. 1977 Mar 12;51(11):341-7.

Abstract

Five patients suffering from non-Hodgkin's lymphoma associated with an intense infiltration of epithelioid histiocytes and even sarcoid-type granulomas in the involved tissue are described. A similar tissue reaction, at both involved and uninvolved sites, has been described in patients with Hodgkin's disease. The cause of this reaction may be immunological; its prognostic significance still awaits elucidation. In the case of non-Hodgkin's lymphomas, it may cause difficulty in diagnosis of lymphoma and hence may result in unnecessary delay in the initiation of therapy.

摘要

本文描述了5例非霍奇金淋巴瘤患者，其受累组织中有大量上皮样组织细胞浸润，甚至出现结节病样肉芽肿。在霍奇金病患者中，已描述了在受累和未受累部位均有类似的组织反应。这种反应的原因可能是免疫性的；其预后意义仍有待阐明。在非霍奇金淋巴瘤的情况下，它可能会导致淋巴瘤诊断困难，从而可能导致治疗开始的不必要延迟。