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The effect of a saturable uptake mechanism on the slopes of dose-response curves for sympathomimetic amines and on the shifts of dose-response curves produced by a competitive antagonist.

作者信息

Langer S Z, Trendelenburg U

出版信息

J Pharmacol Exp Ther. 1969 May;167(1):117-42.

PMID:5772742
Abstract
摘要

相似文献

1
The effect of a saturable uptake mechanism on the slopes of dose-response curves for sympathomimetic amines and on the shifts of dose-response curves produced by a competitive antagonist.一种可饱和摄取机制对拟交感胺剂量-反应曲线斜率以及对竞争性拮抗剂所产生的剂量-反应曲线位移的影响。
J Pharmacol Exp Ther. 1969 May;167(1):117-42.
2
Agonist-antagonist interactions in the normal and supersensitive nictitating membrane of the spinal cat.脊髓猫正常和超敏性瞬膜中的激动剂-拮抗剂相互作用。
J Pharmacol Exp Ther. 1967 May;156(2):207-14.
3
Reserpine-induced depletion of the norepinephrine stores: is it a reliable criterion for the classification of the mechanism of action of sympathomimetic amines?利血平引起的去甲肾上腺素储备耗竭：它是拟交感胺类药物作用机制分类的可靠标准吗？
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4
Effects of dopamine and alpha-methyl-dopamine on smooth muscle and on the cardiac pacemaker.多巴胺和α-甲基多巴胺对平滑肌及心脏起搏器的作用。
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5
Intraneuronal and extraneuronal accumulation of sympathomimetic amines in the isolated nictitating membrane of the cat.猫离体瞬膜中拟交感胺的神经元内和神经元外蓄积
J Pharmacol Exp Ther. 1970 Aug;174(2):290-306.
6
The effects of tyramine on the isolated nictitating membrane of the cat.
J Pharmacol Exp Ther. 1968 Aug;162(2):263-9.
7
On the pharmacology of guanoxan.关于胍生的药理学
Arzneimittelforschung. 1969 Jun;19(6):947-51.
8
Stimulant action of tolazoline on the nictitating membrane of the pithed cat.妥拉唑啉对去脑猫瞬膜的兴奋作用。
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9
Methoxamine as a tool to assess the importance of intraneuronal uptake of l-norepinephrine in the cat's nictitating membrane.甲氧明作为一种工具，用于评估猫瞬膜中去甲肾上腺素的神经元内摄取的重要性。
J Pharmacol Exp Ther. 1970 Mar;172(1):91-9.
10
Decrease in effectiveness of phenoxybenzamine after chronic denervation and chronic decentralization of the nictitating membrane of the pithed cat.去脑猫瞬膜慢性去神经支配和慢性去中枢支配后苯氧苄胺效能的降低
J Pharmacol Exp Ther. 1968 Oct;163(2):290-9.

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Label-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitors.无标记高通量筛选测定法，用于鉴定去甲肾上腺素转运体（NET/SLC6A2）抑制剂。
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2
Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli.浓度-反应曲线和浓度加和曲线之间时变交叉现象的作用机制：以磺胺类药物-红霉素混合物对大肠杆菌的研究为例。
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3
In memoriam: Ullrich Georg Trendelenburg (31 December 1922-21 November 2006).
Naunyn Schmiedebergs Arch Pharmacol. 2007 Jun;375(4):231-40. doi: 10.1007/s00210-007-0160-z.
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Chronic decentralization potentiates neurovascular transmission in the isolated rat tail artery, mimicking the effects of spinal transection.慢性去传入作用增强了离体大鼠尾动脉中的神经血管传递，模拟了脊髓横断的效应。
J Physiol. 2004 Dec 1;561(Pt 2):583-96. doi: 10.1113/jphysiol.2004.074948. Epub 2004 Oct 14.
5
Adrenergic supersensitivity of the scorbutic iris.坏血病性虹膜的肾上腺素能超敏反应。
Trans Am Ophthalmol Soc. 1973;71:536-57.
6
Role of the alpha-adrenoceptor in regulating noradrenaline overflow by nerve stimulation. 1971.α-肾上腺素能受体在通过神经刺激调节去甲肾上腺素溢出中的作用。1971年。
Br J Pharmacol. 1997 Feb;120(4 Suppl):361-77; discussion 358-60. doi: 10.1111/j.1476-5381.1997.tb06817.x.
7
No evidence for functional imidazoline receptors on locus coeruleus neurons.无证据表明蓝斑核神经元上存在功能性咪唑啉受体。
Naunyn Schmiedebergs Arch Pharmacol. 1996 Apr;353(5):557-63. doi: 10.1007/BF00169176.
8
Analysis of the activity of alpha 1-adrenoceptor antagonists in rat aorta.大鼠主动脉中α1肾上腺素能受体拮抗剂活性分析
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9
Differences in sensitivity of rat mesenteric small arteries to agonists when studied as ring preparations or as cannulated preparations.当以环行标本或插管标本形式进行研究时，大鼠肠系膜小动脉对激动剂的敏感性差异。
Br J Pharmacol. 1994 Jun;112(2):579-87. doi: 10.1111/j.1476-5381.1994.tb13114.x.
10
Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade.由于α1-肾上腺素能受体阻滞，多培沙明和非诺多泮引起肾血管舒张。
Br J Pharmacol. 1995 May;115(2):349-55. doi: 10.1111/j.1476-5381.1995.tb15884.x.