Haerer A F, Gotshall R A, Conneally P M, Dyken M L, Poskanzer D C, Price T R, Swanson P D, Calanchini P R
JAMA. 1977 Jul 11;238(2):142-6.
Variations in therapy for patients with complaints suggesting transient ischemic attacks (TIAs) among six participating medical centers are described. Selected treatment, based on clinical interpretation of patient characteristics, varied widely among centers. Therefore, results cannot be attributed to specific treatment. Nevertheless, there was little difference between treatment categories and the likelihood of further TIAs. The mortality of the patients who had received anticoagulants was significantly higher (P less than .001) than those patients receiving other treatment. Possible reasons for these differences are discussed.
本文描述了六个参与研究的医疗中心对疑似短暂性脑缺血发作(TIA)患者的治疗差异。基于对患者特征的临床判断所选择的治疗方法,在各中心之间差异很大。因此,研究结果不能归因于特定的治疗方法。然而,治疗类别与再次发生TIA的可能性之间几乎没有差异。接受抗凝治疗的患者死亡率显著高于接受其他治疗的患者(P<0.001)。文中讨论了这些差异可能的原因。