兔沙眼病原体所致眼部病变
Ocular lesions induced by the trachoma agent in rabbits.
作者信息
Oh J O, Tarizzo M L
出版信息
J Bacteriol. 1969 Mar;97(3):1042-7. doi: 10.1128/jb.97.3.1042-1047.1969.
Abstract
Injection of the T'ang strain of trachoma agent into the anterior chamber of the rabbit eye caused corneal opacity, characteristic microscopic lesions of the corneal endothelium, varying degrees of neovascularization of the cornea, and uveitis. These ocular changes were agent-specific. The experimental data showed that the microorganism developed in the ocular tissues. The results of this study suggest the possibility of using the rabbit eye as an experimental model for the study of trachoma.
摘要
将沙眼病原体的汤氏菌株注入兔眼前房，可导致角膜混浊、角膜内皮特征性的微观病变、角膜不同程度的新生血管形成以及葡萄膜炎。这些眼部变化具有病原体特异性。实验数据表明该微生物在眼组织中生长。本研究结果提示将兔眼用作沙眼研究的实验模型的可能性。
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引用本文的文献
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Protective effect of a synthetic polynucleotide complex (poly I: C) on ocular lesions produced by trachoma agent in rabbits.
Infect Immun. 1970 Jun;1(6):566-73. doi: 10.1128/iai.1.6.566-573.1970.
2
Growth of trachoma agent in primary cultures of rabbit corneal endothelial cells.
J Bacteriol. 1969 Mar;97(3):1502-3. doi: 10.1128/jb.97.3.1502-1503.1969.
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