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破裂性真菌性动脉瘤:一种静脉药物滥用的并发症。

Ruptured mycotic aneurysm: a complication of parenteral drug abuse.

作者信息

Yellin A E

出版信息

Arch Surg. 1977 Aug;112(8):981-6. doi: 10.1001/archsurg.1977.01370080079013.

DOI:10.1001/archsurg.1977.01370080079013
PMID:577679
Abstract

Mycotic aneurysms occurred in five narcotics addicts treated between 1969 and 1975. Fever, localized tenderness, swelling, loss of distal pulses, and leukocytosis were common findings. The aneurysms were located in the femoral (two patients), brachial (two), and superior mesenteric arteries (one). They occurred at the site of arterial injection in three patients. In one patient with subacute bacterial endocarditis, an aneurysm of the superior mesenteric artery developed. In one patient, the pathogenesis was uncertain. All patients had rupture of the arterial wall, with hemorrhage contained by adjacent muscle or soft tissue. Four patients were treated by ligation and debridement. One, with preexisting ischemia, required amputation below the knee. One patient underwent repair with autogenous artery. Recurrent hemorrhage necessitated ligation of the artery. In all patients, extensive sepsis and tissue necrosis precluded repair with prosthetic material. All patients survived, without evident of ischemia.

摘要

1969年至1975年间,五名吸毒成瘾者发生了霉菌性动脉瘤。发热、局部压痛、肿胀、远端脉搏消失和白细胞增多是常见表现。动脉瘤位于股动脉(2例患者)、肱动脉(2例)和肠系膜上动脉(1例)。3例患者的动脉瘤发生在动脉注射部位。1例患有亚急性细菌性心内膜炎的患者发生了肠系膜上动脉瘤。1例患者的发病机制尚不确定。所有患者均出现动脉壁破裂,出血被邻近肌肉或软组织包裹。4例患者接受了结扎和清创治疗。1例已有缺血的患者需要在膝下截肢。1例患者接受了自体动脉修复。反复出血需要结扎动脉。在所有患者中,广泛的败血症和组织坏死使无法使用假体材料进行修复。所有患者均存活,无缺血迹象。

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引用本文的文献

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Infected pseudoaneurysms in intravenous drug abusers: Ligation or reconstruction?静脉药物滥用者的感染性假性动脉瘤:结扎还是重建?
Int J Appl Basic Med Res. 2014 Sep;4(Suppl 1):S23-6. doi: 10.4103/2229-516X.140715.
2
Group B streptococcus mycotic aneurysm of the abdominal aorta: report of a case and review of the literature.B 群链球菌致腹主动脉真菌性动脉瘤:1 例报告并文献复习。
Yale J Biol Med. 2012 Mar;85(1):97-104. Epub 2012 Mar 29.
3
Infected false aneurysms of the limbs secondary to chronic intravenous drug abuse: analysis of perioperative considerations and operative outcomes.
慢性静脉药物滥用继发的肢体感染性假性动脉瘤:围手术期考量及手术结果分析
Surg Today. 2007;37(10):837-44. doi: 10.1007/s00595-006-3495-z. Epub 2007 Sep 26.
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[Mycotic visceral artery aneurysm: clinical picture, diagnosis, differential therapy, and discussion of the literature].
Chirurg. 2004 May;75(5):533-40. doi: 10.1007/s00104-004-0828-6.
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Ruptured superior mesenteric artery aneurysm occurring in association with a heterotopic pancreas: report of a case.肠系膜上动脉动脉瘤破裂合并异位胰腺:病例报告
Surg Today. 1999;29(7):656-9. doi: 10.1007/BF02482995.
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Surgical infections in drug addicts.吸毒者的外科感染
World J Surg. 1980 Jul;4(4):403-13. doi: 10.1007/BF02393159.
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Mycotic aneurysm of the superficial femoral artery.股浅动脉霉菌性动脉瘤
Ir J Med Sci. 1983 Mar;152(3):139-40. doi: 10.1007/BF02960055.
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Mycotic aneurysms in intravenous drug abuse: diagnosis and management.静脉药物滥用所致真菌性动脉瘤:诊断与处理
J Natl Med Assoc. 1985 Feb;77(2):99-102.
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