Georgiadis George S, Bessias Nikolaos C, Pavlidis Polyvios M, Pomoni Maria, Batakis Nikolaos, Lazarides Miltos K
Department of Vascular Surgery, Demokritos University Hospital, Alexandroupolis, Greece.
Surg Today. 2007;37(10):837-44. doi: 10.1007/s00595-006-3495-z. Epub 2007 Sep 26.
To discuss the perioperative considerations and operative outcomes of 26 intravenous (i.v.) drug abusers who presented with infected false aneurysms of the limbs.
The subjects were 20 men and 6 women with pseudoaneurysms (mean age 34 years, range 19-53 years). The femoral and brachial arteries were most commonly involved. All patients, except for those with active bleeding, underwent digital subtraction angiography or Doppler ultrasonography, or both. Treatment consisted of excision and ligation of the aneurysm and local debridement, followed by revascularization with a vein graft or vein patch angioplasty.
The presenting symptoms and signs included a pulsatile mass (69%), ischemic pain (23%), active bleeding (38.5%), signs of inflammation (61.5%), and positive blood culture (31%). Bleeding complications developed in two patients, who underwent subsequent extra-anatomic bypass. One of these patients had hip disarticulation and eventually died. None of the remaining patients had claudication or required an amputation. The mean follow-up period was 24 months (range: 3-50 months). Only five (19.2%) patients received drug rehabilitation, whereas the remaining patients admitted to continued drug abuse after discharge from hospital.
Limb salvage with immediate revascularization is safe and achieves functionality; therefore, its use is justified. Recidivism and continued abuse is the usual consequence after discharge from hospital, making recovery difficult.
探讨26例出现肢体感染性假性动脉瘤的静脉药物滥用者的围手术期注意事项及手术结果。
研究对象为20名男性和6名女性假性动脉瘤患者(平均年龄34岁,范围19 - 53岁)。最常累及股动脉和肱动脉。除有活动性出血的患者外,所有患者均接受了数字减影血管造影或多普勒超声检查,或两者都做了。治疗包括切除并结扎动脉瘤及局部清创,随后用静脉移植物或静脉补片血管成形术进行血管重建。
出现的症状和体征包括搏动性肿块(69%)、缺血性疼痛(23%)、活动性出血(38.5%)、炎症体征(61.5%)和血培养阳性(31%)。两名患者出现出血并发症,随后接受了解剖外旁路手术。其中一名患者进行了髋关节离断术,最终死亡。其余患者均无跛行或需要截肢。平均随访期为24个月(范围:3 - 50个月)。只有5名(19.2%)患者接受了戒毒康复治疗,而其余患者出院后承认仍继续滥用药物。
立即进行血管重建以挽救肢体是安全的,且能实现功能恢复;因此,这样做是合理的。复吸和持续滥用药物是出院后的常见后果,使得康复困难。