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Relationship between the duration of anticonvulsant activity of chlordiazepoxide and systemic levels of the parent compound and its major metabolites in mice.

作者信息

Coutinho C B, Cheripko J A, Carbone J J

出版信息

Biochem Pharmacol. 1969 Feb;18(2):303-16. doi: 10.1016/0006-2952(69)90208-1.

DOI:10.1016/0006-2952(69)90208-1
PMID:5778149
Abstract
摘要

相似文献

1
Relationship between the duration of anticonvulsant activity of chlordiazepoxide and systemic levels of the parent compound and its major metabolites in mice.氯氮䓬的抗惊厥活性持续时间与母体化合物及其主要代谢产物在小鼠体内的系统水平之间的关系。
Biochem Pharmacol. 1969 Feb;18(2):303-16. doi: 10.1016/0006-2952(69)90208-1.
2
Distribution and metabolism of 14C-labelled-chlordiazepoxide in mice.14C标记氯氮卓在小鼠体内的分布与代谢
Int J Neuropharmacol. 1968 Jul;7(4):383-9. doi: 10.1016/0028-3908(68)90021-x.
3
Anticonvulsant properties of some benzodiazepines.某些苯二氮䓬类药物的抗惊厥特性。
J Pharmacol Exp Ther. 1966 Mar;151(3):369-75.
4
Tolerance development with chlordiazepoxide in relation to the plasma levels of the parent compound and its main metabolites in mice.
Acta Pharmacol Toxicol (Copenh). 1973;33(4):262-72. doi: 10.1111/j.1600-0773.1973.tb01526.x.
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Pharmacokinetic model for chlordiazepoxide--HCl in the dog.狗体内氯氮䓬盐酸盐的药代动力学模型。
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Autonomic response to pentamethylenetetrazol following trimetadione and benzodiazepines administration.在服用三甲双酮和苯二氮卓类药物后对戊四氮的自主神经反应。
Arch Int Pharmacodyn Ther. 1968 May;173(1):34-43.
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Disposition and anticonvulsant activity of bromazepam in mice.溴西泮在小鼠体内的处置及抗惊厥活性
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Correlation between the duration of the anticonvulsant activity of diazepam and its physiological disposition in mice.
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Chlordiazepoxide metabolism as related to the reduction in the aggressive behaviour of cynomolgus primates.氯氮䓬代谢与食蟹猴灵长类动物攻击行为减少的关系。
Xenobiotica. 1971 May;1(3):287-301. doi: 10.3109/00498257109033177.
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Metabolites of demoxepam, a chlordiazepoxide metabolite, in man.
J Pharm Sci. 1972 Jan;61(1):123-5. doi: 10.1002/jps.2600610128.

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