Wolf R E, Fudenberg H H, Welch T M, Spitler L E, Ziff M
JAMA. 1977 Aug 22;238(8):869-71.
Six patients with Behçet's syndrome were treated with transfer factor (TF) from randomly selected donors. Mucocutaneous symptoms and signs were predominant at the time that TF injections were started. Three patients showed great improvement, one moderate improvement, and one was unresponsive to multiple injections of TF from different donors. One case was uninterpretable because of concomitant administration of high doses of prednisone and chlorambucil and brief treatment with TF. These results indicate that TF therapy may be beneficial in some patients with Behçet's syndrome and that a trial of TF is warranted at least in the absence of severe ocular or neurologic manifestations.
六例白塞氏综合征患者接受了来自随机选择供体的转移因子（TF）治疗。开始注射TF时，皮肤黏膜症状和体征较为突出。三名患者有显著改善，一名患者有中度改善，一名患者对来自不同供体的多次TF注射无反应。一例因同时使用高剂量泼尼松和苯丁酸氮芥以及TF治疗时间短而无法判断。这些结果表明，TF疗法可能对白塞氏综合征的某些患者有益，并且至少在没有严重眼部或神经表现的情况下，有必要进行TF试验。
