Liu H Y, Giday Z, Moore B F
Ann Allergy. 1977 Jul;39(1):1-7.
The feeding of bovine milk to five highly allergic pediatric patients with bilateral family histories of atopy led to transient malabsorption of glucose and fat as well as systemic autonomic functional changes which may be attributable to pharmacologic actions of histamine and/or acetylcholine. It is hypothesized that during allergic reactions endogenously released smooth muscle stimulating neuromediators could provide rapid propulsion of nutrients through the absorbing portion of the gut, leading to suboptimal absorption, and that bovine milk inducible malabsorption in the atopic patients has an immuno-pharmacologic basis in its pathogenesis.
给五名有双侧特应性家族病史的高度过敏儿科患者喂食牛奶，导致葡萄糖和脂肪出现短暂吸收不良以及全身自主神经功能改变，这可能归因于组胺和/或乙酰胆碱的药理作用。据推测，在过敏反应期间，内源性释放的平滑肌刺激神经介质可促使营养物质快速通过肠道吸收部分推进，导致吸收欠佳，并且特应性患者中牛奶诱导的吸收不良在其发病机制上具有免疫药理学基础。
