Robbins H, Goldman A L
Am Rev Respir Dis. 1977 Aug;116(2):325-6. doi: 10.1164/arrd.1977.116.2.325.
A 53-year-old patient with lymphoblastic lymphoma developed progressive interstitial pulmonary infiltrates. The patient was believed to have Pseudomonas bronchitis and was given parenteral gentamicin. Transbronchial lung biopsy performed through a fiberoptic bronchoscope was complicated by the development of Pseudomonas septicemia. The organism isolated on blood culture, like the one isolated on sputum culture, was fully susceptible to gentamicin in vitro. A prophylactic antimicrobial drug did not prevent bacteremic Pseudomonas infection in our immunosuppressed patient with pre-existent Pseudomonas bronchitis.
一名53岁的淋巴细胞性淋巴瘤患者出现进行性间质性肺浸润。该患者被认为患有铜绿假单胞菌支气管炎,并接受了庆大霉素胃肠外给药。通过纤维支气管镜进行的经支气管肺活检因发生铜绿假单胞菌败血症而出现并发症。血培养分离出的病原体与痰培养分离出的病原体一样,在体外对庆大霉素完全敏感。预防性抗菌药物未能预防我们这位患有先前存在的铜绿假单胞菌支气管炎的免疫抑制患者发生菌血症性铜绿假单胞菌感染。