Geyer H, Afting E G, Müller U
Arch Gynakol. 1977 May 29;222(3):231-8. doi: 10.1007/BF00717600.
In post partum rat uteri, the wet weight, the soluble protein and the DNA content were measured for ten days following delivery. After a lag period of 48 h, the weight and protein content of whole uteri decreased in parallel to one twelfth of the initial values. The DNA content did not change significantly. Hypoplasia contributed not more than 20% to the weight loss, so that at least 80% of the loss was due to hypotrophy. The protein content per cell nucleus (mg protein/mg DNA) decreased by 85% within 10 days. In non-pregnant control animals, uterus weight and protein content per cell nucleus were greater than those of animals measured on the tenth post partum day. In contrast, the protein concentration of the tissue (mg protein/g wet weight) was lower in the control group. It is suggested that this hyperinvolution is caused by the low estrogen levels of the lactating animals.
在产后大鼠子宫中，分娩后十天测量其湿重、可溶性蛋白和DNA含量。经过48小时的延迟期后，整个子宫的重量和蛋白质含量平行下降至初始值的十二分之一。DNA含量没有显著变化。发育不全对体重减轻的贡献不超过20%，因此至少80%的体重减轻是由于萎缩。每细胞核的蛋白质含量（毫克蛋白质/毫克DNA）在10天内下降了85%。在未怀孕的对照动物中，子宫重量和每细胞核的蛋白质含量高于产后第十天测量的动物。相反，对照组中组织的蛋白质浓度（毫克蛋白质/克湿重）较低。有人认为这种过度退化是由泌乳动物雌激素水平低引起的。
