Thurston J G
Postgrad Med J. 1969 Mar;45(521):163-9. doi: 10.1136/pgmj.45.521.163.
In successive years since the opening of a Coronary Care Unit at Westminster Hospital the mortality has been 26 and 20% and for the first 4 months of 1968, 5·3%. Overall mortality for 260 patients was 20%. Resuscitation has been successful in 59% of cardiac arrests within the unit and in 27% of those outside the unit caused by myocardial infarction. Seventeen patients left hospital alive and well who presumably would not have survived had they been treated at home. Given efficient nursing staff and a resuscitation team, there can no longer be any justification for the treatment of patients with myocardial infarction anywhere other than in a coronary care unit, where such facilities are made available, providing admission is arranged within 3 days of the infarcting episode. The disadvantage of an ambulance journey to a patient with a recent infarct after this period of time may outweigh the advantage incurred by the coronary care unit. The Peel Coronary Prognostic Index remains a very useful guide to prognosis in spite of this author's attempts to demonstrate any inaccuracies in its predictions. A high (20%) ‘misdiagnosis’ rate must be accepted if some patients with myocardial infarction are not to be excluded from the unit. The occurrence of 435 deaths reported to Her Majesty's Coroner for Westminster in the relevant period due to myocardial infarction suggests that the time may be ripe for a ‘flying squad’ resuscitation service in London.
自威斯敏斯特医院冠心病监护病房开放后的连续几年里,死亡率分别为26%和20%,1968年的前4个月为5.3%。260名患者的总体死亡率为20%。在该病房内发生的心脏骤停中,复苏成功率为59%,在病房外由心肌梗死导致的心脏骤停中,复苏成功率为27%。17名患者康复出院,若他们在家接受治疗,可能无法存活。若有高效的护理人员和复苏团队,只要在梗死发作后3天内安排入院,且冠心病监护病房具备相应设施,那么除了在冠心病监护病房外,没有任何理由在其他地方治疗心肌梗死患者。在此时间段后,用救护车运送近期梗死患者的弊端可能超过冠心病监护病房带来的益处。尽管作者试图证明皮尔冠心病预后指数预测存在不准确之处,但它仍是非常有用的预后指导指标。若不将一些心肌梗死患者排除在病房之外,就必须接受高达20%的“误诊”率。在相关时期,向威斯敏斯特女王验尸官报告的因心肌梗死死亡的人数为435人,这表明伦敦开展“快速反应小组”复苏服务的时机可能已经成熟。