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[在冠心病监护病房或普通心脏病房治疗的急性心肌梗死患者:一项对比研究]

[Patients with an acute myocardial infarct treated in a coronary unit or in a general cardiology ward A comparative study].

作者信息

Anguita M, Bueno G, López-Granados A, Mesa D, Dios F, Bergillos F, Torres F, Giménez D, Suaárez de Lezo J, Vallés F

机构信息

Servicio de Cardiología, Hospital Universitario Reina Sofía, Córdoba.

出版信息

Rev Esp Cardiol. 1993 Nov;46(11):735-42.

PMID:8290775
Abstract

INTRODUCTION AND OBJECTIVES

Coronary care units have been accepted as the standard location for treatment for patients with acute myocardial infarction. Nevertheless, controversy over their clinical impact, current role and cost-effectiveness still remains. Due to the increased incidence of coronary artery disease in Spain, coronary care units are often full, and patients with acute myocardial infarction must be cared for in a general cardiology ward.

METHODS

We have studied the features and results of 420 patients with acute myocardial infarction consecutively admitted to our hospital and compared patients cared for in the coronary care unit (329 [78%]) with those cared for in the cardiology ward (91 [22%]). Admission to cardiology ward or coronary care unit was based on the clinical judgment of emergency room physicians and the bed availability. No differences in age, sex, risks factors, prior history of coronary heart disease, blood pressure on admission, extension and complications of myocardial infarction were found between both groups.

RESULTS

The percentage of patients with evolved and non-Q wave acute myocardial infarction, and admission electrocardiogram not suggestive of infarction was significantly higher in ward group (23 versus 2.4%, p < 0.001; 19 versus 11%, p < 0.01; and 43 versus 15%, p < 0.01; respectively). Although patients admitted to the coronary care unit underwent intravenous thrombolysis and coronary artery revascularization procedures in a higher proportion, mortality was similar in both groups (14% for ward patients and 17% for coronary care unit patients). When patients with evolved or non-Q wave infarctions and those with admission electrocardiograms not suggestive of infarction were excluded from the analysis, mortality rates remained similar. Subgroups mortality was in general similar for patients cared for in cardiology ward or in coronary care unit, although patients without shock, with Killip class I or II, and older than 70 years, had a slightly lesser mortality when treated in the Cardiology ward (5 versus 11%, 6 versus 11%, and 14 versus 28%, respectively). By contrast, patients with shock, Killip class III or IV, and electrocardiogram at admission not suggestive of infarction, had a lesser mortality when cared for in coronary care unit.

CONCLUSIONS

We conclude that some subgroups of patients with acute myocardial infarction can be, if needed, effective and safely cared for in cardiology ward.

摘要

引言与目的

冠心病监护病房已被公认为急性心肌梗死患者的标准治疗场所。然而,关于其临床影响、当前作用和成本效益的争议仍然存在。由于西班牙冠心病发病率上升,冠心病监护病房常常满员,急性心肌梗死患者必须在普通心脏病病房接受治疗。

方法

我们研究了我院连续收治的420例急性心肌梗死患者的特征和结果,并将在冠心病监护病房接受治疗的患者(329例[78%])与在心脏病病房接受治疗的患者(91例[22%])进行了比较。入住心脏病病房或冠心病监护病房是基于急诊医生的临床判断和床位可用性。两组在年龄、性别、危险因素、冠心病既往史、入院时血压、心肌梗死范围和并发症方面均未发现差异。

结果

病房组中已发生和非Q波急性心肌梗死患者以及入院心电图不提示梗死的患者百分比显著更高(分别为23%对2.4%,p<0.001;19%对11%,p<0.01;43%对15%,p<0.01)。尽管入住冠心病监护病房的患者接受静脉溶栓和冠状动脉血运重建术的比例更高,但两组死亡率相似(病房患者为14%,冠心病监护病房患者为17%)。当将已发生或非Q波梗死患者以及入院心电图不提示梗死的患者排除在分析之外时,死亡率仍然相似。心脏病病房或冠心病监护病房治疗的患者亚组死亡率总体相似,尽管无休克、Killip分级为I或II且年龄大于70岁的患者在心脏病病房治疗时死亡率略低(分别为5%对11%、6%对11%和14%对28%)。相比之下,有休克、Killip分级为III或IV且入院心电图不提示梗死的患者在冠心病监护病房治疗时死亡率较低。

结论

我们得出结论,一些急性心肌梗死患者亚组在必要时可在心脏病病房得到有效且安全的治疗。

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